Chicken Pesto Alfredo Lasagna is a delightful twist on traditional lasagna, combining the rich flavors of chicken, savory pesto, and creamy Alfredo sauce. This scrumptious dish is not only packed with protein but also makes for a healthy, comforting meal that will satisfy everyone at your table. Whether you’re looking for a cozy dinner or a meal prep option for the week, Chicken Pesto Alfredo Lasagna hits all the right notes!

Why make this Chicken Pesto Alfredo Lasagna recipe

Protein-rich: With 2.5 lbs of chicken breast, this dish is a great source of lean protein.
Quick prep: Enjoy a delicious lasagna with minimal effort and time in the kitchen.
Meal-prep friendly: Prepare in advance and savor throughout the week.
Low-carb option: A guilt-free indulgence without compromising on flavor.
Kid-approved: An irresistible dish that even picky eaters will devour.

"This is the best lasagna I’ve ever made! My family asks for it all the time." – A satisfied cook.

How to make Chicken Pesto Alfredo Lasagna

Making Chicken Pesto Alfredo Lasagna is straightforward and doesn’t require fancy equipment, just a few mixing bowls and a baking dish. If you love fast protein breakfasts, try our Cottage Cheese Pancakes for another delicious option!

Ingredients

2.5 lbs. chicken breast
4 Tbsp basil pesto
2 Tbsp white miso
1 cup chicken bone broth
2 Tbsp salt
2 Tbsp Italian seasoning
1 Tbsp garlic powder
2 tsp onion powder
1 tsp black pepper
4 cups blended cottage cheese
1/2 cup reduced-fat cream cheese
1.5 cups freshly grated Parmesan
2 cups reduced-fat mozzarella
2 Tbsp chopped parsley
16 oz no-boil lasagna noodles
2 cups reduced-fat mozzarella (for topping)
1/2 cup Parmesan (for topping)
2 Tbsp pesto (for topping)

When preparing Chicken Pesto Alfredo Lasagna, feel free to substitute ingredients per your dietary needs; for instance, you could replace chicken with a plant-based protein for a vegetarian option.

Directions

Preheat: the oven to 375°F (190°C).
Mix: together the chicken breast, basil pesto, white miso, chicken bone broth, salt, Italian seasoning, garlic powder, onion powder, and black pepper in a large bowl.
Combine: in another bowl the blended cottage cheese, reduced-fat cream cheese, Parmesan, mozzarella, and chopped parsley to create the Alfredo sauce.
Layer: in a greased pan, the no-boil lasagna noodles, followed by a layer of the chicken mixture, then a layer of the Alfredo sauce. Repeat the layers until all ingredients are used, finishing with a layer of noodles topped with remaining mozzarella and Parmesan.
Spread: the final layer with 2 Tbsp of pesto.
Cover: with foil and bake for 25-30 minutes. Remove the foil and bake for an additional 15-20 minutes until the cheese is bubbly and golden.
Let: cool for a few minutes before serving. Enjoy your cozy bake!

How to serve Chicken Pesto Alfredo Lasagna

Serve your Chicken Pesto Alfredo Lasagna hot out of the oven, garnished with additional chopped parsley for a pop of color. This dish pairs excellently with a crisp side salad or garlic bread for a complete meal. For a nutritious kick, try our Southwest Chicken Salad on the side.

How to store

Store any leftovers in the refrigerator for up to 4 days in an airtight container. You can also freeze portions of Chicken Pesto Alfredo Lasagna for up to a month. To reheat, defrost overnight in the fridge and warm in the oven at 350°F (175°C) until heated through.

For safe storage timing, see USDA FoodData Central.

Tips to make

Chicken options: You can cook the chicken ahead of time for quicker assembly.
Cheese substitutions: Swap out reduced-fat cheese for full-fat varieties for a creamier texture.
Add veggies: Sautéed spinach or mushrooms can be great additions for extra flavor and nutrients.
Don’t skip resting: Allow the lasagna to cool for 10 minutes post-baking to help it hold its shape when serving.

Variations

Vegetarian: Substitute chicken with roasted vegetables or a plant-based meat alternative.
Dairy-free: Use cashew cream or silken tofu instead of cheeses.
Gluten-free: Opt for gluten-free lasagna noodles to make this dish suitable for gluten-sensitive individuals.

FAQs

Can I meal prep Chicken Pesto Alfredo Lasagna?

Yes, Chicken Pesto Alfredo Lasagna keeps well for 3–4 days in the fridge; store in an airtight container.

Can I freeze leftovers?

Freeze portions for up to a month; thaw overnight, then reheat gently.

What substitutions work best?

Swap chicken for a plant-based protein or adjust cheese types to fit your dietary restrictions.

For nutrition insights, visit Healthline.

Chicken Pesto Alfredo Lasagna is a must-try recipe that brings comfort and healthy flavors to your table. Don’t forget to share your thoughts in the comments below; we’d love to hear from you!